Relationships between differentially expressed miRNAs, putative target genes, and functions. Network and pathway analysis using Pathway Studio 5 shows the relationships among the significantly differentially expressed miRNAs, potential target genes (expression cutoff log2 ratio ≥± 0.4), and biological functions and disorders implicated by the differentially expressed target genes. Up-regulated genes and miRNAs are in red; down-regulated genes and miRNAs are in green.
Sarachana et al. Genome Medicine 2010 2:23 doi:10.1186/gm144